Secondary Prevention of Atherosclerosis Through Chlamydia pneumoniae Eradication (SPACE Trial): A Randomised Clinical Trial in Patients with Peripheral Arterial Disease
نویسندگان
چکیده
منابع مشابه
Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): randomised placebo-controlled trial.
BACKGROUND Excess cardiovascular mortality has been documented in chronic haemodialysis patients. Oxidative stress is greater in haemodialysis patients with prevalent cardiovascular disease than in those without, suggesting a role for oxidative stress in excess cardiovascular disease in haemodialysis. We investigated the effect of high-dose vitamin E supplementation on cardiovascular disease ou...
متن کاملO-30: Novel Interventions to Reduce ReInfection in Women with Chlamydia: A Randomised-Controlled Trial
Background: To determine if postal testing kits (PTK) and patient delivered partner therapy (PDPT) for managing sexual partners of women with Chlamydia tracho-matis, reduce re-infection rates in women, compared to partner notification by patient referral. Materials and Methods: Three hundred and thirty women testing positive for chlamydia, at clinics for genitourinary medicine, family planning ...
متن کاملlower extremity arterial calcification as a predictor of coronary atherosclerosis in patients with peripheral arterial disease
conclusion peripheral arterial calcification is significantly correlated with cad extent in patients with pad. peripheral arterial calcification can be a useful marker for predicting multivessel-cad. results lecs in multivessel-cad were significantly higher than those in nonsignificant cad (10.0 ± 5.8 versus 4.0 ± 3.1, p < 0.001). lecs significantly correlated with ccs (r = 0.831, p < 0.001) an...
متن کاملPatients with peripheral arterial disease in the CHARISMA trial.
AIMS The aim of this study was to determine whether clopidogrel plus aspirin provides greater protection against major cardiovascular events than aspirin alone in patients with peripheral arterial disease (PAD). METHODS AND RESULTS This is a post hoc analysis of the 3096 patients with symptomatic (2838) or asymptomatic (258) PAD from the CHARISMA trial. The rate of cardiovascular death, myoca...
متن کاملChlamydia pneumoniae DNA in the arterial wall of patients with peripheral vascular disease.
BACKGROUND Chlamydia pneumoniae is a human respiratory pathogen that has recently been related to the genesis of symptomatic atherosclerosis. C. pneumoniae has been studied more widely in relation to coronary atherosclerosis than to peripheral arterial occlusive disease (PAOD). The present study aimed to retrospectively analyze the presence of C. pneumoniae DNA in patients with PAOD. MATERIAL...
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ژورنال
عنوان ژورنال: European Journal of Vascular and Endovascular Surgery
سال: 2005
ISSN: 1078-5884
DOI: 10.1016/j.ejvs.2005.01.001